Constructed in 1901 based on a design by architect Alexandru Bernardazzi and commissioned by Princess Natalia Dadiani, this building has a rich history. Prior to its construction, the site held an old real estate property, which State Councilor Mitrofan Purișkevici sold to the Council of the girls’ gymnasium. Princess Dadiani founded and directed the institution until her passing in 1903. Subsequently, the building served as the location for girls’ gymnasium no. 2 during World War II, sustaining severe damage in the process.

Post-war, the structure underwent reconstruction and, until 1964, functioned as the headquarters of the Central Committee of the Communist Party of the MSSR. Later, it became the Palace of the Pioneers, with its left wing housing the Republican Society “The Science.”

In 1976, the building was repurposed to host the Museum of History of the Communist Party of Moldova. To augment the exhibition space, a two-level wing, mirroring the one on the left, was added. Today, the building is home to the National Art Museum of Moldova, boasting a significant heritage of 39,000 works of art.