The museum is situated within the house where the renowned Soviet architect Alexei Shchusev (1873-1949) was born and lived for 24 years. Erected in 1851-1853, this building is now recognized as a monument of national architectural and historical significance, duly recorded in the Register of Monuments of History and Culture of the municipality of Chisinau.

The museum’s origin dates back to 1947 when Alexei Shchusev himself organized the Museum of Soviet Architecture. It was initially curated with drawings, models, documents, and letters from the architect’s personal archive. However, the museum did not withstand the test of time and was dismantled in the early 1950s.

In 1973, on the occasion of the great architect’s 100th anniversary, the museum was rejuvenated. A permanent exhibition dedicated to the life and work of Alexei Shchusev was inaugurated, and it continues to operate to this day.

Additionally, the museum hosts a mini-exhibition paying homage to another notable personality—Alexandro Bernardazzi, the first official architect of Chisinau (1831-1907).